Fortigel® is a collagen peptide that has been effectively ‘cut’ to match the receptor sites within cartilage tissues. When consumed, it helps stimulate chondrocytes — the cells responsible for cartilage maintenance.9

Collagen Synthesis™contains 5 grams of Fortigel®, the clinically supported dosage for supporting cartilage maintenance.

Tendoforte® has a molecular weight that matches the receptor sites in tendons and ligaments. It helps produce more fibroblasts. These are the cells responsible for synthesizing new collagen and maintaining the structural framework of connective tissue.9

Fibroblasts also play a crucial role in the tissue healing process, making Tendoforte® especially effective at improving the strength and stability of tendons and ligaments. 

Each serving of Collagen Synthesis™ contains the clinically supported 5-gram dosage of Tendoforte®.

Supplementing with vitamin C supports optimal collagen formation and reduces oxidative damage from exercise-induced tissue stress.10, 11

 In cases of vitamin C deficiency, collagen fibers cannot repair properly and lack adhesion strength. More importantly, your body can’t form or store collagen without vitamin C, making it a crucial cofactor in collagen formation. 

A 2019 pilot study published in the International Journal of Sport Nutrition and Exercise Metabolism showed that taking vitamin C with collagen peptides before training doubled collagen synthesis rates in the exercising joints.12

When you take hyaluronic acid with collagen peptides, you get a synergistic joint-building response. That’s because hyaluronic acid works with collagen to provide a moisture-rich environment within joint structures.13 This enables collagen fibers to stretch without breaking, improving their resilience and reducing fiber tears during the critical tissue remodeling phase of tissue recovery. 

This is vital to rebuilding, as fragile new collagen fibers need time to stretch and align properly without breaking down. 

Studies show supplementing with hyaluronic acid: 

• Provides structural support for collagen-producing fibroblasts14

• Improves synovial fluid effusion in joints and reduces joint discomfort15 

• Improves joint strength (52 mg of hyaluronic acid helped healthy subjects with mild joint discomfort improve their knee strength)16

Collagen Synthesis™ contains 80 mg of hyaluronic acid to bolster the collagen-rebuilding process. 

Choline-Stabilized Orthosilicic acid is a highly absorbable form of the mineral silicon. Silicon plays a pivotal role in collagen synthesis within joints, bone mineralization, and overall immune health. Even though silicon is one of the most abundant minerals on the planet, most people don’t get enough. 

That’s because it doesn’t accumulate in the body. Multiple studies have shown that silicon supplementation improves joint, bone, and skin health.17 

Studies indicate that combining choline-stabilized orthosilicic acid with collagen peptides may stimulate collagen production and connective tissue repair more than either ingredient would on its own.18

Because it appears to support tissue remodeling when combined with collagen, we included 10 mg of choline-stabilized orthosilicic acid in every serving of Collagen Synthesis™. This is the most bioavailable form of the mineral and the most targeted method of supporting collagen maintenance, rebuilding, and longevity.